Acetaminophen – Tylenol for chronic pain

In new research doctors examined the use of Tylenol for chronic pain.

Doctors acknowledge that Acetaminophen (paracetamol) is the most commonly used painkiller worldwide and recommended as first-line treatment in all pain conditions by the World Health Organization.

In the new study, researchers performed a systematic literature review to evaluate the efficacy of acetaminophen when used for chronic pain conditions.

In the research they reviewed – all studies were conducted in patients with hip- or knee osteoarthritis and six out of seven studies had observation periods of less than three months.

All included studies showed no or little efficacy with dubious clinical relevance.

In conclusion, there is little evidence to support the efficacy of acetaminophen treatment in patients with chronic pain conditions.1

1. Ennis ZN, Dideriksen D, Vaegter HB et al. Acetaminophen for Chronic Pain: A Systematic Review on Efficacy.  Basic Clin Pharmacol Toxicol. 2015 Nov 17. doi: 10.1111/bcpt.12527. [Epub ahead of print]