Systematic Review of Dextrose Prolotherapy for Chronic Musculoskeletal Pain

Literature Review | Systematic Review of Dextrose Prolotherapy for Chronic Musculoskeletal Pain

This is a brief review of

Hauser RA, Lackner JB, Steilen-Matias D, Harris DK. A Systematic Review of Dextrose Prolotherapy for Chronic Musculoskeletal Pain. Clinical Medicine Insights Arthritis and Musculoskeletal Disorders. 2016;9:139-159. doi:10.4137/CMAMD.S39160.

The authors have published much literature on the use of Prolotherapy as a nonsurgical regenerative injection technique.

Study Highlights

  • Dextrose prolotherapy is supported in the treatment of tendinopathies in patients who fail conservative therapies;
  • Dextrose prolotherapy is supported in the treatment of knee osteoarthritis and finger joints in patients who do not respond to conservative therapies;
  • Dextrose prolotherapy is supported in the treatment of spinal and pelvic pain in patients who fail to respond to conservative therapies;
  • The efficacy of dextrose prolotherapy in myofascial pain cannot be determined from a single randomized control trial.
  • Overall, dextrose prolotherapy has been demonstrated to be effective and should be considered as a treatment for pain and dysfunction associated with chronic musculoskeletal conditions, particularly tendinopaties and osteoarthritis.

In this systematic review, Caring Medical and Rehabilitation Services researchers evaluated 32 studies on dextrose prolotherapy for chronic musculoskeletal pain.

Overall dextrose prolotherapy has been demonstrated to be efficacious and should be considered as a treatment for pain and dysfunction associated with chronic musculoskeletal conditions, particularly tendinopaties and osteoarthritis.