Prolotherapy research for tennis elbow pain

Prolotherapy: Regenerative Medicine for Lateral Epicondylitis

Lateral Epicondylopathy is a pain at the outer side of the elbow. Prolotherapy is a regenerative injection technique that stimulates the repair of injured tissue. In this case, the elbow attachments.

Prolotherapy: Regenerative Medicine for Lateral Epicondylitis

December 2020: Case Reports Turkish journal of anaesthesiology and reanimation.

In this case report, a case of lateral epicondylitis, diagnosed with clinical and ultrasound examination, found that ultrasound guided Prolotherapy treatment alleviated pain “and the tendon was restored.”  The patient previously had local steroid injections which provided relief only for a limited time.

Dextrose Prolotherapy Versus Normal Saline Injection for the Treatment of Lateral Epicondylopathy

September 2020: Journal of alternative and complementary medicine. (2)

In this study researchers compared the effect of dextrose prolotherapy with saline in the treatment of chronic lateral epicondylopathy.

  • Sixty cases of chronic Lateral Epicondylopathy participants were included in the study.
  • Participants were randomly divided into two groups as dextrose prolotherapy and normal saline.
  • Saline or hypertonic dextrose (15%) was injected at the baseline, and at the end of the 4th and 8th week.
  • Assessments were performed at baseline, and at the end of the 4th, 8th, and 12th week.
  • Outcome measures: Primary outcome measures were Visual Analog Scale (VAS) for pain, Patient Rated Tennis Elbow Evaluation (PRTEE-Total [PRTEE-T], PRTEE-Pain, PRTEE-Function); secondary outcome measures were Disabilities of the Arm, Shoulder, and Hand Score (DASH) and pain-free handgrip strength.

Results: Intragroup analysis demonstrated that both groups significantly improved in Visual Analog Scale, Patient Rated Tennis Elbow Evaluation, Disabilities of the Arm, Shoulder, and Hand Score scores, and handgrip strength during the study period.

  • Intergroup analysis showed that Patient Rated Tennis Elbow Evaluation score changes between baseline-4th and -12th week;
  • Visual Analog Scale at rest change between baseline and 4th week in the dextrose prolotherapy group were significantly higher than the saline group
  • There was no significant difference between groups in Visual Analog Scale, Disabilities of the Arm, Shoulder, and Hand Score, and handgrip strength between any time points, in terms of improvement.
  • Conclusion: Our study results showed that dextrose prolotherapy outperformed saline in Patient Rated Tennis Elbow Evaluation. Although saline seems to be a comparable clinical effect with DPT, further studies comparing the effects of saline injection and dextrose prolotherapy are necessary, in chronic Lateral Epicondylopathy.

Reference:

1 Akcay S, Gurel Kandemir N, Kaya T, Dogan N, Eren M. Dextrose Prolotherapy Versus Normal Saline Injection for the Treatment of Lateral Epicondylopathy: A Randomized Controlled Trial. J Altern Complement Med. 2020 Sep 28. doi: 10.1089/acm.2020.0286. Epub ahead of print. PMID: 32990454. [Pubmed] [Google Scholar]

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