Conclusions |
The Hackett-Hemwall technique of dextrose Prolotherapy used on patients who had an average duration of four years of unresolved foot pain, who were eighteen months out from their last Prolotherapy session, was shown in this observational study to improve quality of life. The patients reported less pain, stiffness, depressed and anxious thoughts, medication usage, as well as improved walking ability, sleep and exercise ability. This included patients who were told by their medical doctor(s) there were no other treatment options for their unresolved foot pain. Further research is needed to confirm the results found in this retrospective study. Although studies with larger patient populations in more controlled settings are needed to properly document the efficacy of Hackett-Hemwall dextrose Prolotherapy, this treatment should be seriously considered for people suffering with unresolved foot and toe pain based on risk/reward parameters.
BIBLIOGRAPHY
| 1. | Hawke F, et al. Understanding the nature and mechanism of foot pain. Journal of Foot and Ankle Research. 2009;2:1. |
| 2. | Mann R. Pain in the foot. Postgraduate Medicine. 1987;82:154-174. |
| 3. | Warren B. Plantar fasciitis in runners, treatment and prevention. Sports Med. 1990;10:338-345. |
| 4. | Hawke F, et al. Understanding the nature and mechanism of foot pain. Journal of Foot and Ankle Research. 2009;2:1. |
| 5. | Meatarsalgia. Mayo foundation for medical education and research. Mayoclinic.com. Available at: http://www.mayoclinic.com/health/metatarsalgia/DS00496. Updated 1/24/2009. Accessed 5/11/2010. |
| 6. | Asad A, et al. Common foot disorders. Clinical Medicine and Research. 2005 May; 3(2):116-119. |
| 7. | Burks J. How to treat severe bunions. Podiatry Today. 2005;18:8. |
| 8. | Scranton, P. Metarsalgia: diagnosis and treatment. J Bone J Surg Am. 1980;62:723. |
| 9. | Wu KK. Morton interdigital neuroma: a clinical review of its etiology, treatment and results. Journal of Foot and Ankle Surgery. 1996;Mar-Apr.35(2):112-9; discussion;187-8. |
| 10. | Lee D, et al. Foot and ankle surgery: considerations for the geriatric patient. J Am Board of Fam Med. 2009;22(3):316-324. |
| 11. | Benvenuti F. Foot pain and disability in older persons: An epidemiologic survey. J Am Geriatr Soc. 1995;43:479-484. |
| 12. | Alternative treatments: Dealing with chronic pain. Mayo Clinic Health Letter. April 2005;23(4). |
| 13. | Lennard T. Pain Procedures in Clinical Practice. Second Edition. Philadelphia, PA. Hanley & Belfus, Inc., 2000. |
| 14. | Wheaton M, et al. The ligament connection to osteoarthritis. Journal of Prolotherapy. 2010;2:1:294-304. |
| 15. | Hackett G, et al. Ligament and Tendon Relaxation Treated by Prolotherapy, 5th ed. Oak Park, IL. Gustav A. Hemwall, 1992. |
| 16. | Reeves KD. Prolotherapy: Present and future applications in soft tissue pain and disability. Phys Med Rehabil Clin North Am. 1995;6:917-926. |
| 17. | Kayfetz D. Occipital-cervical (whiplash) injuries treated by prolotherapy. Medical Trial Technique Quarterly. 1963;June:9-29. |
| 18. | Ongley MJ, et al. A new approach to the treatment of chronic low back pain. The Lancet. 1987;July:143-147. |
| 19. | Echow E. A Randomized, double-blind, placebo-controlled trial of sclerosing injections in patients with chronic low back pain. Rheumatology. Oxford. 1999;38(12):1255-9. |
| 20. | Klein RG, et al. A Randomized double-blind trial of dextrose-glycerine-phenol injections for chronic low back pain. Journal of Spinal Disorders. 1993;6(1):23-33. |
| 21. | Yelland MJ. Prolotherapy injections, saline injections and exercises for chronic low back pain: A randomized trial. Spine. 2004;29(1):9-16. |
| 22. | Hackett G. Referral pain and sciatica in diagnosis of low back disability. Journal of the American Medical Association. 1957;163:183-185. |
| 23. | Hackett G. Ligament and Tendon Relaxation Treated by Prolotherapy. Third Edition. Springfield, IL. Charles C. Thomas. 1958. |
| 24. | Schwarz R. Prolotherapy: A literature review and retrospective study. Journal of Neurology, Orthopedic Medicine and Surgery. 1991;12:220-229. |
| 25. | Schmidt H. Effect of growth factors on proliferation of fibroblasts from the medial collateral and anterior cruciate ligaments. Journal of Orthopaedic Research. 1995;13:184-190. |
| 26. | Hackett G. Joint stabilization: An experimental, histiologic study with comments on the clinical application in ligament proliferation. American Journal of Surgery. 1955;89:968-973. |
| 27. | Hackett G. Back pain following trauma and disease – Prolotherapy. Military Medicine. 1961;July:517-525. |
| 28. | Hauser R, et al. Prolo Your Pain Away! Third Edition. Oak Park, IL. Beulah Land Press. 2007;139-147. |
| 29. | Hauser R, et al. Prolo Your Pain Away! Third Edition. Oak Park, IL. Beulah Land Press: 2007;21-22. |
| 30. | Martin E. Pharmacologic management of foot pain in the older patient. J Am Podiatr Med Assoc. 2004;94(2):98-103. |
| 31. | Ottawa panel evidence-based clinical practice guidelines for therapeutic exercises and manual therapy in the management of osteoarthritis. Phys Ther. 2005;85(9):907-71. |
| 32. | Jannink M. Effectiveness of custom-made orthopaedic shoes in the reduction of foot pain and pressure in patients with degenerative disorders of the foot. Foot Ankle Int. 2006;27(11):974-9. |
| 33. | Reeves K. Prolotherapy: basic science, clinical studies and technique. In: Lennard TA, ed: Pain Procedures in Clinical Practice. 2nd ed. Philadelphia, PA: Hanley and Belfus. 2000;172-190. |
| 34. | Metatarsalgia: foot and ankle disorders. Merck manual professional. Available at: http://www.merck.com/mmpe/sec04/ch043/ch043d.html. Accessed on May 13, 2010. Revised March 2008 by Whitney, KA. |
| 35. | Stainsby GD. Pathological anatomy and dynamic effect of the displaced plantar plate and the importance of the integrity of the plantar plate-deep transverse metatarsal ligament tie-bar. Ann R Coll Surg Engl. 1997;79:58-61. |
| 36. | Liu Y. An in situ study of the influence of a sclerosing solution in rabbit medial collateral ligaments and its junction strength. Connective Tissue Research. 1983;2:95-102. |
| 37. | Maynard J. Morphological and biomechanical effects of sodium morrhuate on tendons. Journal of Orthopaedic Research. 1985; 3:236-248. |
| 38. | Hauser R, et al. Prolo Your Pain Away! Third Edition. Oak Park, IL. Beulah Land Press. 2007;126-138. |
| 39. | Alderman D. Prolotherapy for knee pain. Practical Pain Management. 2007; July/August: 70-79. |
| 40. | Hollinshead W. Functional Anatomy of the Limb and Back. 5th Ed. Philadelphia, PA. W. B. Saunders. 316-338. |
| 41. | Reeves KD, et al. Randomized prospective double-blind placebo-controlled study of dextrose Prolotherapy for knee osteoarthritis with or without ACL laxity. Alternative Therapies. 2000;6(2):68-80. |
 |
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