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Statistical AnalysisA matched sample paired t-test was used to calculate the difference in responses between the before and after measures for pain, stiffness and range of motion for the 94 hips, including the subgroup of twenty patients who before starting Prolotherapy were told there were no other treatment options and the eight patients told by their medical doctor(s) there was no other treatment option but surgery. Using the paired t-test, all p values for pain for all subgroups reached statistical significance at the p<.0001 level. For the 94 hips, the p values for pain, stiffness, and range of motion all showed statistically significant improvements at the p<.0001 level. |
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Prolotherapy Overview
- What is Prolotherapy?
- Questions and Answers
- Prolotherapy and Pain
- Do Injections Hurt?
- Prolotherapists Are Not All the Same
- Ideal Candidate
- Number of Treatments
- Prolotherapy Injections
- Prolotherapy and Surgery
- Soreness After Prolotherapy
- When Prolotherapy Doesn't Work
- Proof That Prolotherapy Is Working
- Results Not Seen Immediately
- Stimulates Normal Healing
- Regenerates Cartilage
- Arthritis Pain
- Connective Tissue
- Platelet Rich Plasma
- Why Platelet Rich Plasma?
- Strains and Sprains
- Risks With Prolotherapy
- Will Prolotherapy Affect Blood Tests?
Prolotherapy Research
- Prolotherapy Case Studies/Patient Reports
- Prolotherapy Research
- Scientific Editorials
- The Acceleration of Articular Cartilage Degeneration in Osteoarthritis by NSAIDs
- NSAIDs Introduction
- Articular Cartilage Anatomy
- The Extent of the Problem
- The Animal Data
- Human Studies
- NSAIDs Inhibit Prostaglandin Synsthesis
- NSAIDs Accelerate the Radiographic Progression
- NSAIDs Increase the Need for Joint Replacement
- Overall Effects of NSAIDs on Osteoarthritic Joints
- Recommendations on the Use of NSAIDs
- NSAIDs Bibliography
- The Regeneration of Articular Cartilage with Prolotherapy
- Deterioration of Articular Cartilage in Osteoarthritis by Corticosteroid Injections
- Introduction
- Animal Studies
- Corticosteroids Induce Premature Cell Death of Chondrocytes in Articular Cartilage
- Deterioration of Articular Cartilage With Just One Steriod Injection
- Corticosteroids Cause Cartilage Deterioration in Exercised Horses
- Human Data
- Articular Cartilage Deterioration Not Due To Aging
- Natural Course of Asteoarthritis of the Knee Treated With or Without Intraarticular Corticosteroid Injections
- Corticosteroid Inhibition of Human Articular Cartilage Biosynthesis
- Intraarticuler Corticosteroid Usage is Common
- General Guidelines for Intrarticular Costicosteroid Usage in Osteoarthritis of a Joint
- Conclusion
- Bibliography
- The Acceleration of Articular Cartilage Degeneration in Osteoarthritis by NSAIDs

