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Ligament Repair with Prolotherapy


One of the reasons that we perform Prolotherapy at the bone-ligament junction is due to the fact that ligaments do not heal well on their own like muscles do. Ligaments have extremely poor blood flow. This results in very slow healing and recovery from ligament injuries, hence the need for treatments that stimulate healing. We recently came across an article from The Joint and Diseases Research Group at the University of Calgary in Alberta, Canada that outlined what we have been seeing at Caring Medical for years related to ligament injuries. The authors compiled these four attributes that effect the healing of ligament injuries.1


1. Combined injuries have poorer prognosis.

This statement has been discovered and rediscovered several times 2. It is one of the most commonly used when deciding the chances of an injured ligament healing in a timely fashion.

2. Different ligaments heal differently.

Not all ligaments heal at the same rate, or have the same potential for healing. The ACL in the knee is recognized as the ligament which takes the longest to heal, if it fully heals at all. If a person injures the ACL, the chances of more injuries and the eventual development of osteoarthritishave been published in many different studies. 3,4 In contrast to this, theMCL heals rather quickly, and has a better history for untreated injuries to be better than untreated ACL injuries. 5,6This could be for any number of reasons, but there are suggestions that the joint mechanics are more favorable to the MCL than the ACL.

3. Ligament healing is variable and unpredictable.

Since ligaments are so important to the mechanics of our body, the healing process is varied and unable to be planned. The doctor can make the assumption that the ligament will heal if the patient avoids x, y and z, but variables in the patient’s life that neither the doctor nor the patient can account for often exist. 5,6

4. Ligament healing is slow and can fail late in the process.

Early successes in the treatment of injured ligaments are common, but not to be trusted. Complete failure of the ligament has been reported even after it was supposedly repaired. This failure has been shown to be late in the healing process, happening any time from three to five years after the “repair”.

What does this all mean for Prolotherapy?

The fact is, someone who gets Prolotherapy for their ligament, tendon, or joint injury will not have to deal with the above four problems explained here. It does not matter if you have one injury or five; Prolotherapy is able to addressnearly every kind of ligament injury.  Ross Hauser, MD can help your ACL and your MCL, and not worry about the chance of more injuries in the future. The healing stimulated by Prolotherapy is predictable. At Caring Medical, we do hundreds of treatments in very short amounts of time. We have seen complete healing in ligaments that have been failing the patient over and over again, for years. There is not a risk for chronic re-injury as there are for traditional treatments.

How is Prolotherapy different from traditional treatments?

Prolotherapy works with the body to stimulate its natural healing processes. Dr. Hauser injects a dextrose-based solution into the injured areas and this stimulates a mild inflammatory response at the injection site(s). Because the body heals by inflammation, it signals the body that healing needs to take place. The body believes that because of the inflammation, the body is re-injured. The body increases the blood flow to that area, and heals the weakened ligament by creating new collagen. When collagen matures, it shrinks. As it shrinks, it tightens the stretched ligaments, repairing the damage. This is not a temporary solution, nor is it a pain management solution. Prolotherapy can be a permanent solution to your pain.

If this sounds like a treatment that you or a loved one could benefit from, contact us at 708.848.7789 or in another way by clicking here. If you would like to make an appointment, click here.


  1. Bray, R.C., Frank, C.B., Shrive N.G. Ligament Healing a Review of Some Current Clinical and Experimental Concepts. The Iowa Orthopaedic Journal. Vol 12: 21-28.
  2. O’Donoghue, D.H.:Surgical Treatment of Fresh Injuries to the Major Ligaments of the Knee. J. Bone Joint Surg. 32A:721, 1950.
  3. Bray, R.C., Frank, C.B., Shrive N.G., et al.: Joint Instability Alters Scar Quantity and Quality in a Healing Rabbit Ligament. Orthop. Trans. 14:322, 1990.
  4. Fetto, J.F., Marchall, J.L., The Natural History and Diagnosis of Anterior Cruciate Ligament Insufficiency. Clin. Orthop. 147:29, 1980.
  5. Ellsasser, J.C., Reynolds, F.C., Omshundro, J.R.: The Non-operative Treatment of Collateral Ligaments of the Knee in Professional Football Players. J. Bone Joint Surg. 56A:1185, 1974.
  6. Hastings, D.E.: The Non-operative Management of Collateral Ligament Injuries of the Knee Joint. Clin. Orthop. 147:22, 1980.


  1. Michael Orr says:

    Hi, about 2 and a half years ago, I fell one story to an asphalt driveway, landing on my left foot stifflegged. Perhaps unfortunately, I seem to have strong bones. They never break so ligaments and tendons absorb the energy for them. In this incident, nearly all of the force went into my left ankle. I have sufficiently recovered from all other injuries I have sustained through my life, but this ankle, was (I think) damaged too much for the healing to last. Maybe I just need to find a way to get rest, but I also have to strengthen don’t I? This injury has been a real challenge. Please let me know what you think regarding the prolotherapy treatment as well as any other thoughts. You should know that there seems to be plenty of inflamation, though no notable swelling. There never was signnificant swelling but stiffness and widespread spraining and straining. Most of the current trouble is in the upper front of my ankle. There is also some pain in the muscles and perhaps tendons in that area. Thank You

    • Dear Michael,
      Sorry to hear you are going through all of this. As you know, the body heals by inflammation. When the body or body part is inflamed, it is the body’s response to injury. Prolotherapy induces healing in the body and causes a local inflammation in the injected area. You may or may not have inflammation remaining. IE your pain may be due to a weak ligament as you suggest. This may actually not be an inflamed ligament, but a degenerated one. The only way we know of to stimulate this to heal is with Prolotherapy. Here is a link to the study we performed on ankle pain patients: If you are interested in becoming a patient of Dr. Hauser’s we would be happy to see you here. Give us a call at 708-848-7789 or

      The team at AboutProlotherapy

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